Concentration: 10 mg/vial
Purity: ≥99%
Form: Lyophilized powder
Molecular Formula: C₂₆₅H₄₀₄N₇₂O₈₂S₁
Molecular Weight: 2171.37 g/mol
CAS Number: 1334177-21-6
Storage: Store lyophilized powder at -20°C. Reconstituted solution should be kept refrigerated (2–8°C) and used within a short period for optimal stability. Protect from light.

MOTS-c is a mitochondrial-derived peptide (MDP) that has drawn increasing interest in metabolic and longevity research. Unlike traditional peptides encoded in nuclear DNA, MOTS-c originates from mitochondrial DNA, highlighting the unique signaling role of mitochondria in regulating whole-body physiology.

In preclinical research, MOTS-c has been studied for its ability to influence cellular metabolism, insulin sensitivity, and energy regulation. It has been shown to activate AMPK pathways, supporting healthy metabolic function in experimental models. Because of this, MOTS-c is of particular interest in studies on obesity, type 2 diabetes, and age-related metabolic decline.

Additionally, MOTS-c has been explored for its potential roles in exercise performance, cellular stress response, and protection against metabolic dysfunction. By linking mitochondrial signaling to systemic energy balance, it provides researchers with a unique tool for studying mitochondrial-nuclear communication and its effects on health and aging.