Nicotinamide Mononucleotide (NMN): 1,000mg

Key Benefits:

• Boosts NAD+ Levels: NMN is a direct precursor to NAD+, an essential molecule for energy production and cellular repair. By replenishing NAD+, NMN combats age-related declines in mitochondrial function and supports optimal metabolism.
• Supports Longevity Pathways: NMN activates sirtuins, enzymes that regulate DNA repair, inflammation control, and cellular health.
• Enhances Physical and Cognitive Performance: Higher NAD+ levels improve endurance, recovery, and brain function.

Scientific Evidence:

• Studies show NMN supplementation restores NAD+ levels, improving mitochondrial function and lifespan in animal models[1]
• Human trials demonstrate NMN's ability to enhance blood flow and muscle oxygenation[2]

Trimethylglycine (TMG) (as Betaine Anhydrous): 500mg

Key Benefits:

• Supports Methylation Processes: TMG acts as a methyl donor, critical for processing homocysteine into methionine. This helps maintain healthy DNA and supports NMN's conversion into NAD+.
• Protects Cells from Stress: TMG stabilizes proteins and cell membranes under osmotic stress, ensuring cellular integrity.
• Supports Heart and Liver Health: Helps support homocysteine levels and cardiovascular risk factors.

Scientific Evidence:

• Research highlights TMG's role in enhancing cellular methylation and metabolic efficiency[3][4]
• TMG improves physical endurance and energy production in athletes[5]

Pterostilbene: 50mg

Key Benefits:

• Antioxidant Powerhouse: A more bioavailable analog of resveratrol, pterostilbene neutralizes free radicals and protects against oxidative damage.
• Activates Sirtuins: Supports longevity by enhancing sirtuin activity, which depends on NAD+.
• Supports Cognitive Function: Protects brain cells from age-related decline, enhancing memory and focus.

Scientific Evidence:

• Studies suggest pterostilbene is more bioavailable and effective than resveratrol at promoting cellular health[6][7]
• Pterostilbene has anti-inflammatory effects, supporting cardiovascular and brain health[8]

Apigenin: 50mg

Key Benefits:

• Inhibits CD38: Apigenin blocks CD38, an enzyme that depletes NAD+ levels, ensuring more NAD+ is available for critical cellular processes.
• Anti-Inflammatory Properties: Supports chronic inflammation, a key driver of aging and age-related diseases.
• Protects Against Oxidative Stress: Enhances cellular resilience by reducing oxidative damage to DNA, proteins, and lipids.

Scientific Evidence:

• Research confirms apigenin's ability to inhibit CD38 and increase NAD+ availability[9][10]
• Apigenin also shows neuroprotective effects, supporting healthy brain aging[11]

The Synergy of Science

By combining these four powerhouse ingredients, NMN 1000+ supports NAD+ production through multiple pathways:

• NMN: Directly replenishes NAD+ levels.
• TMG: Facilitates NMN metabolism via methylation.
• Pterostilbene: Protects and enhances NAD+ and Sirtuin activity.
• Apigenin: Reduces NAD+ depletion by inhibiting CD38.

*This is a statement of nutritional support. This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any diseases. Individual results may vary.